Description
SS-31 Peptide:
With a unique characteristic of holding a cationic 3+ charge at physiological pH. This molecule appears to permeate cell membranes with ease and potentially traverses the blood-brain barrier. It has been suggested to rapidly exit cells, despite not being a substrate for P-glycoprotein.
One of the most researched attributes of SS-31 is its potential to accumulate in the inner mitochondrial membrane at concentrations that appear to be over 1000 times greater than in plasma. In this environment, SS-31 50mg may interact with cardiolipin, an anionic phospholipid unique to the inner mitochondrial membrane.
Researchers suggest that this binding disrupts the interactions between cardiolipin and cytochrome C.This leads to a reduction in the oxidative inactivation of cardiolipin by cytochrome C. The mechanism of SS-31 peptide may involve inhibiting the peroxidase activity of cytochrome c. While preserving Met80-heme ligation and favoring its electron carrier activity. Given that researchers suggest cardiolipin plays a pivotal role in optimizing mitochondrial electron transport and ATP production. This disruption has significant potential.
At Pepsynth Labs, our SS-31 (50mg) attracts attention in mitochondrial studies that explore cellular energy potential.







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